N-[(1S)-2-Hydroxy-1-Methylethyl]-2-nitrobenzenesulfonaMide - Names and Identifiers
N-[(1S)-2-Hydroxy-1-Methylethyl]-2-nitrobenzenesulfonaMide - Physico-chemical Properties
Molecular Formula | C9H12N2O5S
|
Molar Mass | 260.27 |
Density | 1.424±0.06 g/cm3(Predicted) |
Boling Point | 458.4±55.0 °C(Predicted) |
pKa | 9.97±0.50(Predicted) |
Storage Condition | Sealed in dry,Store in freezer, under -20°C |
N-[(1S)-2-Hydroxy-1-Methylethyl]-2-nitrobenzenesulfonaMide - Introduction
(S)-N-(o-nitrobenzenesulfonyl)-2-aminopropanol is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
(S)-N-(o-nitrobenzenesulfonyl)-2-aminopropanol is a solid having a white to pale yellow color. It has a high melting and boiling point and is soluble in some organic solvents such as dichloromethane and ethanol. This compound is chiral and exists as two mirror-image isomers:(R)-N-(o-nitrobenzenesulfonyl)-2-aminopropanol and (S)-N-(o-nitrobenzenesulfonyl)-2-aminopropanol.
Use:
(S)-N-(o-nitrobenzenesulfonyl)-2-aminopropanol is widely used in organic synthesis. It is often used as a chiral inducer to catalyze asymmetric synthesis reactions. In addition, it can also be used to prepare other organic compounds, such as pharmaceutical intermediates and pesticides.
Preparation Method:
The preparation method of (S)-N-(o-nitrobenzenesulfonyl)-2-aminopropanol is to react 2-aminopropanol with N-benzylnitrobenzenesulfonamide under appropriate conditions. Generally, this reaction needs to be carried out under an inert atmosphere to avoid oxidation or other side reactions. The synthetic product can be purified by crystallization or column chromatography to obtain a pure product.
Safety Information:
Limited information on the safety of (S)-N-(o-nitrobenzenesulfonyl)-2-aminopropanol. As an organic compound, it may have some toxicity. When using or handling, it is necessary to follow appropriate laboratory procedures and avoid contact with skin, eyes and inhalation. Personal protective equipment such as lab gloves and eye protection should be used if necessary. For specific safety information and hazards, refer to the relevant Chemical Safety Data Sheet (MSDS) or consult with the supplier.
Last Update:2024-04-09 21:54:55